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Fei Y, Cao X, Liu J. Nutritional competition within tumor microenvironment dictates anti-tumor immunity. Natl Sci Rev. 2023 Nov 1;11(2):nwad277.
[PubMed]
Jiang Y, Sun S, Quan Y, Wang X, You Y, Zhang X, Zhang Y, Liu Y, Wang B, Xu H, Cao X. Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response. Nat Commun. 2023 Dec 20;14(1):8455.
[PubMed]
Zhu J, Liu S, Fang J, Cui Z, Wang B, Wang Y, Liu L, Wang Q, Cao X. Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response. Cell Rep. 2023 Oct 31;42(10):113192.
[PubMed]
Zhang L, Dong Y, Zhang L, Wang M, Zhou Y, Jia K, Wang S, Wang M, Li Y, Luo S, Lu S, Fan Y, Zhang D, Yang Y, Li N, Yu Y, Cao X, Hou J. Mitochondrial IRG1 traps MCL-1 to induce hepatocyte apoptosis and promote carcinogenesis. Cell Death Dis. 2023 Sep 22;14(9):625.
[PubMed]
Wu J, Hu Y, Song J, Xu J, Zhang Q, Chai Y, Wang X, Wang B, Zhao Y, Cao X, Xu X. Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation. Cell Death Dis. 2023 Sep 6;14(9):592.
[PubMed]
Zhang B, Wang CM, Wu HX, Wang F, Chai YY, Hu Y, Wang BJ, Yu Z, Xia RH, Xu RH, Cao XT. MFSD2A potentiates gastric cancer response to anti-PD-1 immunotherapy by reprogramming the tumor microenvironment to activate T cell response. Cancer Commun (Lond). 2023 Oct;43(10):1097-1116.
[PubMed]
Huang J, Yu Z, Li X, Yang M, Fang Q, Li Z, Wang C, Chen T, Cao X. E3 ligase HECTD3 promotes RNA virus replication and virus-induced inflammation via K33-linked polyubiquitination of PKR. Cell Death Dis. 2023 Jul 4;14(7):396.
[PubMed]
Zhang X, Liu J, Cheng Y, Chen K, Chen Y, Zhu H, Li Z, Liu S, Cao X. Metabolic enzyme Suclg2 maintains tolerogenicity of regulatory dendritic cells diffDCs by suppressing Lactb succinylation. J Autoimmun. 2023 Jul:138:103048.
[PubMed]
Liu J, Cao X. Glucose metabolism of TAMs in tumor chemoresistance and metastasis. Trends Cell Biol. 2023 Nov;33(11):967-978.
[PubMed]
Liu W, Wang Z, Liu S, Zhang X, Cao X, Jiang M. RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex. Cell Rep. 2023 Feb 28;42(2):112097.
[PubMed]
Zhang S, Cao X. TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus. Trends Immunol. 2023 Mar;44(3):153-155.
[PubMed]
Liu J, Cheng Y, Zhang X, Chen Y, Zhu H, Chen K, Liu S, Li Z, Cao X. Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell Rep. 2023 Jan 31;42(1):111991.
[PubMed]
Liu J, Cao X. RBP-RNA interactions in the control of autoimmunity and autoinflammation. Cell Res. 2023 Feb;33(2):97-115.
[PubMed]
Lou H, Zheng J, Fang XL, Liang Z, Zhang M, Chen Y, Wang C, Cao X. Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant. Cell Res. 2023 Jan;33(1):80-82.
[PubMed]

Zhou W, Wang J, Wang X, Wang B, Zhao Z, Fu J, Wang Y, Zhang X, Zhu P, Jiang M, Cao X. Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses. Sci Signal. 2022 Dec 20;15(765):eabo4356.
[PubMed]
Li Z, Chen X, Dan J, Hu T, Hu Y, Liu S, Chai Y, Shi Y, Wu J, Ni H, Zhu J, Wu Y, Li N, Yu Y, Wang Z, Zhao J, Zhong N, Ren X, Shen Z, Cao X. Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents. Signal Transduct Target Ther. 2022 Nov 16;7(1):377.
[PubMed]
Li Z, Zhou Y, Jia K, Yang Y, Zhang L, Wang S, Dong Y, Wang M, Li Y, Lu S, Zhang W, Zhang L, Fan Y, Zhang D, Li N, Yu Y, Cao X, Hou J. JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis. J Hematol Oncol. 2022 Nov 4;15(1):161.
[PubMed]
Shi Q, Shen Q, Liu Y, Shi Y, Huang W, Wang X, Li Z, Chai Y, Wang H, Hu X, Li N, Zhang Q, Cao X. Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance. Cancer Cell. 2022 Oct 10;40(10):1207-1222.e10.
[PubMed]
Lou H, Ling GS, Cao X. Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target. J Autoimmun. 2022 Oct:132:102861.
[PubMed]
Liu J, Zhang X, Cao X. Dendritic cells in systemic lupus erythematosus: From pathogenesis to therapeutic applications. J Autoimmun. 2022 Oct:132:102856.
[PubMed]
Lou H, Cao X. Antibody variable region engineering for improving cancer immunotherapy. Cancer Commun (Lond). 2022 Sep;42(9):804-827.
[PubMed]
Wang Z, Zhu J, Liu Y, Wang Z, Cao X, Gu Y. Tumor-polarized GPX3⁺ AT2 lung epithelial cells promote premetastatic niche formation. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201899119.
[PubMed]
Chen Y, Liu J, Zhang X, Zhu H, Wang Y, Li Z, Liu Y, Liu S, Liu S, Li N, Chen K, Cao X. lncRNA-GM targets Foxo1 to promote T cell-mediated autoimmunity. Sci Adv. 2022 Aug 5;8(31):eabn9181.
[PubMed]
Zhu H, Chen K, Chen Y, Liu J, Zhang X, Zhou Y, Liu Q, Wang B, Chen T, Cao X. RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis. Signal Transduct Target Ther. 2022 Jul 20;7(1):240.
[PubMed]
Liu Y, Song R, Zhao L, Lu Z, Li Y, Zhan X, Lu F, Yang J, Niu Y, Cao X. m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration. Signal Transduct Target Ther. 2022 Jun 29;7(1):194.
[PubMed]
Wang C, Zhou W, Liu Y, Xu Y, Zhang X, Jiang C, Jiang M, Cao X. Nuclear translocation of RIG-I promotes cellular apoptosis. J Autoimmun. 2022 Jun:130:102840.
[PubMed]
Ma Z, Zhou Y, Wang Y, Xu Y, Liu Y, Liu Y, Jiang M, Zhang X, Cao X. RNA-binding protein hnRNP UL1 binds κB sites to attenuate NF-κB-mediated inflammation. J Autoimmun. 2022 May:129:102828.
[PubMed]
Li P, Liu Y, Song R, Zhao L, Yang J, Lu F, Cao X. RNA 2 '-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response. Front Immunol. 2022 Apr 7:13:793582.
[PubMed]
Wang X, Zhang Q, Cao X. Reversing epigenetic repression of transposable elements for improving tumor immunogenicity. Cancer Commun (Lond). 2022 Mar;42(3):266-268.
[PubMed]

Xu J, Wang P, Li Z, Li Z, Han D, Wen M, Zhao Q, Zhang L, Ma Y, Liu W, Jiang M, Zhang X, Cao X. IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation. Cell Rep. 2021 Nov 2;37(5):109926.
[PubMed]
Cao X. ISG15 secretion exacerbates inflammation in SARS-CoV-2 infection. Nat Immunol. 2021 Nov;22(11):1360-1362.
[PubMed]
Lu F, Cao X. Dissolving the cytosolic bacteria in non-immune cells. Trends Immunol. 2021 Nov;42(11):943-944.
[PubMed]
Chen T, Cao X. cGAS-like receptors: ancient catchers of viral nucleic acids. Trends Immunol. 2021 Nov;42(11):945-947.
[PubMed]
Yang X, Wang B, Cao X. Transcriptional suppression of CD8+ T cell exhaustion for improving T cell immunotherapy. Cancer Commun (Lond). 2021 Nov;41(11):1228-1231.
[PubMed]
Liu J, Zhang X, Cheng Y, Cao X. Dendritic cell migration in inflammation and immunity. Cell Mol Immunol. 2021 Nov;18(11):2461-2471.
[PubMed]
Liu S, Liu J, Yang X, Jiang M, Wang Q, Zhang L, Ma Y, Shen Z, Tian Z, Cao X. Cis-acting lnc-Cxcl2 restrains neutrophil-mediated lung inflammation by inhibiting epithelial cell CXCL2 expression in virus infection. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2108276118.
[PubMed]
Hu Y, Wang X, Song J, Wu J, Xu J, Chai Y, Ding Y, Wang B, Wang C, Zhao Y, Shen Z, Xu X, Cao X. Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages. Cell Death Dis. 2021 Jul 27;12(8):743.
[PubMed]
Wang Z, Wang B, Cao X. Epigenetic checkpoint blockade: new booster for immunotherapy. Signal Transduct Target Ther. 2021 Jul 22;6(1):281.
[PubMed]
Qian C, Cao X. Reversing the mitochondrial stress-induced exhaustion of CD8+ T cells for improving cancer immunotherapy. Cell Mol Immunol. 2021 Jul;18(7):1634-1637.
[PubMed]
Cong B, Cui Z, Cao X. Identification of immune-activating metabolite for enhancing T cell therapy of cancer. Cancer Commun (Lond). 2021 Jul;41(7):535-537.
[PubMed]
Zhang Q, Cao X. Epigenetic Remodeling in Innate Immunity and Inflammation. Annu Rev Immunol. 2021 Apr 26:39:279-311.
[PubMed]
Cong B, Zhang Q, Cao X. The function and regulation of TET2 in innate immunity and inflammation. Protein Cell. 2021 Mar;12(3):165-173.
[PubMed]
Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, Li Z, Gu Y, Chen T, Cao X. TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. Signal Transduct Target Ther. 2021 Feb 28;6(1):90.
[PubMed]
Wang Y, Tong Q, Ma SR, Zhao ZX, Pan LB, Cong L, Han P, Peng R, Yu H, Lin Y, Gao TL, Shou JW, Li XY, Zhang XF, Zhang ZW, Fu J, Wen BY, Yu JB, Cao X, Jiang JD. Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota. Signal Transduct Target Ther. 2021 Feb 24;6(1):77.
[PubMed]
Shi Y, Shi Q, Shen Q, Zhang Q, Cao X. Dicer-independent snRNA/snoRNA-derived nuclear RNA 3 regulates tumor-associated macrophage function by epigenetically repressing inducible nitric oxide synthase transcription. Cancer Commun (Lond). 2021 Feb;41(2):140-153.
[PubMed]

Wang Y, Wang P, Zhang Y, Xu J, Li Z, Li Z, Zhou Z, Liu L, Cao X. Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation. Immunity. 2020 Dec 15;53(6):1168-1181.e7.
[PubMed]
Li Z, Zhou Y, Zhang L, Jia K, Wang S, Wang M, Li N, Yu Y, Cao X, Hou J. microRNA-199a-3p inhibits hepatic apoptosis and hepatocarcinogenesis by targeting PDCD4. Oncogenesis. 2020 Oct 24;9(10):95.
[PubMed]
Xia S, Liu X, Cao X, Xu S. T-cell expression of Bruton's tyrosine kinase promotes autoreactive T-cell activation and exacerbates aplastic anemia. Cell Mol Immunol. 2020 Oct;17(10):1042-1052.
[PubMed]
Liu W, Wang Z, Liu L, Yang Z, Liu S, Ma Z, Liu Y, Ma Y, Zhang L, Zhang X, Jiang M, Cao X. LncRNA Malat1 inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23695-23706.
[PubMed]
Lin H, Cao X. Nuclear innate sensors for nucleic acids in immunity and inflammation. Immunol Rev. 2020 Sep;297(1):162-173.
[PubMed]
Song X, Liu S, Wang W, Ma Z, Cao X, Jiang M. E3 ubiquitin ligase RNF170 inhibits innate immune responses by targeting and degrading TLR3 in murine cells. Cell Mol Immunol. 2020 Aug;17(8):865-874.
[PubMed]
Cao X. COVID-19: immunopathology and its implications for therapy. Nat Rev Immunol. 2020 May;20(5):269-270.
[PubMed]
Yi L, Li Z, Hu T, Liu J, Li N, Cao X, Liu S. Intracellular HSP70L1 inhibits human dendritic cell maturation by promoting suppressive H3K27me3 and H2AK119Ub1 histone modifications. Cell Mol Immunol. 2020 Jan;17(1):85-94.
[PubMed]
Chen X, Liu X, Zhang Y, Huai W, Zhou Q, Xu S, Chen X, Li N, Cao X. Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages. Cell Mol Immunol. 2020 Jan;17(1):76-84.
[PubMed]

Xu H, Jiang Y, Xu X, Su X, Liu Y, Ma Y, Zhao Y, Shen Z, Huang B, Cao X. Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA. Nat Immunol. 2019 Dec;20(12):1621-1630.
[PubMed]
Zhang H, Han C, Li T, Li N, Cao X. The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling. Cell Mol Immunol. 2019 Oct;16(10):800-809.
[PubMed]
Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, Xu H, Niu Y, Cao X. N 6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019 Sep 13;365(6458):1171-1176.
[PubMed]
Wang L, Wen M, Cao X. Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses. Science. 2019 Aug 16;365(6454):eaav0758.
[PubMed]
Zhou Y, Li M, Xue Y, Li Z, Wen W, Liu X, Ma Y, Zhang L, Shen Z, Cao X. Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation. Cell Res. 2019 Aug;29(8):641-654.
[PubMed]
Lin H, Jiang M, Liu L, Yang Z, Ma Z, Liu S, Ma Y, Zhang L, Cao X. The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response. Nat Immunol. 2019 Jul;20(7):812-823.
[PubMed]
Zhang Q, Cao X. Epigenetic regulation of the innate immune response to infection. Nat Rev Immunol. 2019 Jul;19(7):417-432.
[PubMed]
He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, Cao Q, Tu X, Pan T, Jiang Z, Cao X, Lai L, Wang Q. Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation. J Clin Invest. 2019 Jun 27;129(9):3877-3893.
[PubMed]
Li T, Qin K, Li N, Han C, Cao X. An endosomal LAPF is required for macrophage endocytosis and elimination of bacteria. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12958-12963.
[PubMed]
Wang H, Hu X, Huang M, Liu J, Gu Y, Ma L, Zhou Q, Cao X. Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. Nat Commun. 2019 Apr 23;10(1):1898.
[PubMed]
Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, Xu S, Thomas T, Li N, Cao X. KAT8 selectively inhibits antiviral immunity by acetylating IRF3. J Exp Med. 2019 Apr 1;216(4):772-785.
[PubMed]
Yu G, Wu Y, Wang W, Xu J, Lv X, Cao X, Wan T. Low-dose decitabine enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by re-modulating the tumor microenvironment. Cell Mol Immunol. 2019 Apr;16(4):401-409.
[PubMed]
Sun D, Cao X, Wang C. Polycomb chromobox Cbx2 enhances antiviral innate immunity by promoting Jmjd3-mediated demethylation of H3K27 at the Ifnb promoter. Protein Cell. 2019 Apr;10(4):285-294.
[PubMed]
Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, Chen Y, Zhu H, Li Z, Cao X. CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis. Immunity. 2019 Mar 19;50(3):600-615.e15.
[PubMed]
Gu Y, Liu Y, Fu L, Zhai L, Zhu J, Han Y, Jiang Y, Zhang Y, Zhang P, Jiang Z, Zhang X, Cao X. Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG. Nat Med. 2019 Feb;25(2):312-322.
[PubMed]
Zhang Y, Wang X, Zhang X, Wang J, Ma Y, Zhang L, Cao X. RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):976-981.
[PubMed]
Liu X, Zhang P, Zhang Y, Wang Z, Xu S, Li Y, Huai W, Zhou Q, Chen X, Chen X, Li N, Wang P, Li Y, Cao X. Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling. Cell Res. 2019 Jan;29(1):42-53.
[PubMed]
Xue Y, Lai L, Lian W, Tu X, Zhou J, Dong P, Su D, Wang X, Cao X, Chen Y, Wang Q. SOX9/FXYD3/Src Axis Is Critical for ER+ Breast Cancer Stem Cell Function. Mol Cancer Res. 2019 Jan;17(1):238-249.
[PubMed]
Xu J, Cao X. Long noncoding RNAs in the metabolic control of inflammation and immune disorders. Cell Mol Immunol. 2019 Jan;16(1):1-5.
[PubMed]

Huang M, Wang H, Hu X, Cao X. lncRNA MALAT1 binds chromatin remodeling subunit BRG1 to epigenetically promote inflammation-related hepatocellular carcinoma progression. Oncoimmunology. 2018 Oct 16;8(1):e1518628.
[PubMed]
Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, Zhao K, Zhang Q, Liu X, Liu J, Liu B, Cao X. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018 Nov 15;175(5):1336-1351.e17.
[PubMed]
Hu X, Wang H, Han C, Cao X. Src promotes anti-inflammatory (M2) macrophage generation via the IL-4/STAT6 pathway. Cytokine. 2018 Nov:111:209-215.
[PubMed]
Li Z, Liu S, Xu J, Zhang X, Han D, Liu J, Xia M, Yi L, Shen Q, Xu S, Lu L, Cao X. Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors. Immunity. 2018 Oct 16;49(4):640-653.e5.
[PubMed]
Wang S, Zhang Q, Wang Q, Shen Q, Chen X, Li Z, Zhou Y, Hou J, Xu B, Li N, Cao X. NEAT1 paraspeckle promotes human hepatocellular carcinoma progression by strengthening IL-6/STAT3 signaling. Oncoimmunology. 2018 Aug 6;7(11):e1503913.
[PubMed]
Wang Q, Wang C, Li N, Liu X, Ren W, Wang Q, Cao X. Condensin Smc4 promotes inflammatory innate immune response by epigenetically enhancing NEMO transcription. J Autoimmun. 2018 Aug:92:67-76.
[PubMed]
Sun W, Shi J, Wu J, Zhang J, Chen H, Li Y, Liu S, Wu Y, Tian Z, Cao X, Li N. A modified HLA-A*0201-restricted CTL epitope from human oncoprotein (hPEBP4) induces more efficient antitumor responses. Cell Mol Immunol. 2018 Aug;15(8):768-781.
[PubMed]
Jiang M, Zhang S, Yang Z, Lin H, Zhu J, Liu L, Wang W, Liu S, Liu W, Ma Y, Zhang L, Cao X. Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response. Cell. 2018 May 3;173(4):906-919.e13.
[PubMed]
Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, Fan J, Zhou W, Qiu S, Zhang Y, Dong T, Li N, Jiang Z, Zhu H, Zhang Q, Ma Y, Zhang L, Wang Q, Yu Y, Li N, Cao X. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018 Apr 19;173(3):634-648.e12.
[PubMed]
Shen Q, Zhang Q, Shi Y, Shi Q, Jiang Y, Gu Y, Li Z, Li X, Zhao K, Wang C, Li N, Cao X. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. Nature. 2018 Feb 1;554(7690):123-127.
[PubMed]
Qian C, Cao X. Dendritic cells in the regulation of immunity and inflammation. Semin Immunol. 2018 Feb:35:3-11.
[PubMed]
Liu X, Su X, Xu S, Wang H, Han D, Li J, Huang M, Cao X. MicroRNA in vivo precipitation identifies miR-151-3p as a computational unpredictable miRNA to target Stat3 and inhibits innate IL-6 production. Cell Mol Immunol. 2018 Feb;15(2):99-110.
[PubMed]
Liu S, Yi L, Ling M, Jiang J, Song L, Liu J, Cao X. HSP70L1-mediated intracellular priming of dendritic cell vaccination induces more potent CTL response against cancer. Cell Mol Immunol. 2018 Feb;15(2):135-145.
[PubMed]
Liu S, Jiang M, Wang W, Liu W, Song X, Ma Z, Zhang S, Liu L, Liu Y, Cao X. Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA. Nat Immunol. 2018 Jan;19(1):41-52.
[PubMed]

Zhu H, Gu Y, Xue Y, Yuan M, Cao X, Liu Q. CXCR2+ MDSCs promote breast cancer progression by inducing EMT and activated T cell exhaustion. Oncotarget. 2017 Dec 7;8(70):114554-114567.
[PubMed]
Wang C, Wang Q, Xu X, Xie B, Zhao Y, Li N, Cao X. The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3. J Exp Med. 2017 Dec 4;214(12):3597-3610.
[PubMed]
Wang P, Xu J, Wang Y, Cao X. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism. Science. 2017 Nov 24;358(6366):1051-1055.
[PubMed]
Zhao C, Jia M, Song H, Yu Z, Wang W, Li Q, Zhang L, Zhao W, Cao X. The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I. Cell Rep. 2017 Nov 7;21(6):1613-1623.
[PubMed]
Cao X. Intestinal inflammation induced by oral bacteria. Science. 2017 Oct 20;358(6361):308-309.
[PubMed]
Zheng Q, Hou J, Zhou Y, Li Z, Cao X. The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus. Nat Immunol. 2017 Oct;18(10):1094-1103.
[PubMed]
Han D, Li J, Wang H, Su X, Hou J, Gu Y, Qian C, Lin Y, Liu X, Huang M, Li N, Zhou W, Yu Y, Cao X. Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression. Hepatology. 2017 Oct;66(4):1151-1164.
[PubMed]
Chen K, Liu J, Cao X. Regulation of type I interferon signaling in immunity and inflammation: A comprehensive review. J Autoimmun. 2017 Sep:83:1-11.
[PubMed]
Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, Hu Y, Wu J, Cao X. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8620-8625.
[PubMed]
Chen K, Liu J, Liu S, Xia M, Zhang X, Han D, Jiang Y, Wang C, Cao X. Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity. Cell. 2017 Jul 27;170(3):492-506.e14.
[PubMed]
Qin K, Han C, Zhang H, Li T, Li N, Cao X. NAD+ dependent deacetylase Sirtuin 5 rescues the innate inflammatory response of endotoxin tolerant macrophages by promoting acetylation of p65. J Autoimmun. 2017 Jul:81:120-129.
[PubMed]
Yang Y, Zhou Y, Hou J, Bai C, Li Z, Fan J, Ng IOL, Zhou W, Sun H, Dong Q, Lee JMF, Lo CM, Man K, Yang Y, Li N, Ding G, Yu Y, Cao X. Hepatic IFIT3 predicts interferon-α therapeutic response in patients of hepatocellular carcinoma. Hepatology. 2017 Jul;66(1):152-166.
[PubMed]
Xia M, Liu J, Liu S, Chen K, Lin H, Jiang M, Xu X, Xue Y, Liu W, Gu Y, Zhang X, Li Z, Yi L, Qian Y, Zhou C, Li R, Zhang X, Li Z, Cao X. Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity. Nat Commun. 2017 Jun 9:8:15818.
[PubMed]
Li X, Zhang Q, Shi Q, Liu Y, Zhao K, Shen Q, Shi Y, Liu X, Wang C, Li N, Ma Y, Cao X. Demethylase Kdm6a epigenetically promotes IL-6 and IFN-β production in macrophages. J Autoimmun. 2017 Jun:80:85-94.
[PubMed]
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D, Cantor H, Gao X, Lu L. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017 May 1;214(5):1453-1469.
[PubMed]
Liu G, Zhou L, Zhang H, Chen R, Zhang Y, Li L, Lu JY, Jiang H, Liu D, Qi S, Jiang YM, Yin K, Xie Z, Shi Y, Liu Y, Cao X, Chen YX, Zou D, Zhang WJ. Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20. Nat Commun. 2017 Mar 22:8:14824.
[PubMed]
Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, Xie Y, Chen S, Dong P, Chen L, Chen Z, Dai F, Wan X, Xiao P, Cao X, Liu Y, Wang Q. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017 Mar 13:8:14654.
[PubMed]
Tang S, Chen T, Yang M, Wang L, Yu Z, Xie B, Qian C, Xu S, Li N, Cao X, Wang J. Extracellular calcium elicits feedforward regulation of the Toll-like receptor-triggered innate immune response. Cell Mol Immunol. 2017 Feb;14(2):180-191.
[PubMed]
Cui B, Lu S, Lai L, Xie Y, He J, Xue Y, Xiao P, Pan T, Chen L, Liu Y, Cao X, Wang Q. Protective function of interleukin 27 in colitis-associated cancer via suppression of inflammatory cytokines in intestinal epithelial cells. Oncoimmunology. 2017 Jan 20;6(2):e1268309.
[PubMed]
Li X, Yang M, Yu Z, Tang S, Wang L, Cao X, Chen T. The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection. Sci Signal. 2017 Jan 3;10(460):eaae0435.
[PubMed]
Ren W, Wang C, Wang Q, Zhao D, Zhao K, Sun D, Liu X, Han C, Hou J, Li X, Zhang Q, Cao X, Li N. Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages. Sci Rep. 2017 Jan 3:7:39986.
[PubMed]

Cao X. Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease. Nat Rev Immunol. 2016; 16(1):35-50. [PubMed]
Liu J, Qian C, Cao X. Post-Translational Modification Control of Innate Immunity. Immunity. 2016; 45(1):15-30. [PubMed]
Liu Y, Gu Y, Han Y, Zhang Q, Jiang Z, Zhang X, Huang B, Xu X, Zheng J, Cao X. Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils. Cancer Cell. 2016; 30(2):243-256. [PubMed]
Liu Y, Cao X. Characteristics and Significance of the Pre-metastatic Niche. Cancer Cell. 2016; 30(5):668-681. [PubMed]
Li X, Zhang Q, Ding Y, Liu Y, Zhao D, Zhao K, Shen Q, Liu X, Zhu X, Li N, Cheng Z, Fan G, Wang Q, Cao X. Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. Nat Immunol. 2016; 17(7):806-815. [PubMed]
Ding Y, Guo Z, Liu Y, Li X, Zhang Q, Xu X, Gu Y, Zhang Y, Zhao D, Cao X. The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation. Nat Immunol. 2016; 17(10):1167-1175. [PubMed]
Liu Y, Cao X. Organotropic metastasis: role of tumor exosomes. Cell Res. 2016; 26(2):149-150. [PubMed]
Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, Zhang L, Zhang J, Cao X. RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci U S A. 2016; 113(34):9581-9586. [PubMed]
Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, Gu Y, Su X, Xia M, Li W, Zhang X, Wang Q, Cao X, Wang J. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. Elife. 2016; 5. pii: e14087. doi:10.7554/eLife.14087. [PubMed]
Zhao D, Zhang Q, Liu Y, Li X, Zhao K, Ding Y, Li Z, Shen Q, Wang C, Li N, Cao X. H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1. Cell Rep. 2016; 15(2):288-299. [PubMed]
Gao Q, Zhang Y, Han C, Hu X, Zhang H, Xu X, Tian J, Liu Y, Ding Y, Liu J, Wang C, Guo Z, Yang Y, Cao X. Blockade of CD47 ameliorates autoimmune inflammation in CNS by suppressing IL-1-triggered infiltration of pathogenic Th17 cells. J Autoimmun. 2016; 69:74-85. [PubMed]
Meng J, Liu X, Zhang P, Li D, Xu S, Zhou Q, Guo M, Huai W, Chen X, Wang Q, Li N, Cao X. Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8. J Autoimmun. 2016; 73:42-53. [PubMed]
Li X, Yang M, Yu Z, Tang S, Wang L, Cao X, Chen T. The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection. Sci Signal. 2017; 10(460). [PubMed]
Hu X, Han C, Jin J, Qin K, Zhang H, Li T, Li N, Cao X. Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression. Sci Rep. 2016; 6:26252. [PubMed]
Ren W, Wang C, Wang Q, Zhao D, Zhao K, Sun D, Liu X, Han C, Hou J, Li X, Zhang Q, Cao X, Li N. Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages. Sci Rep. 2017; 7:39986. [PubMed]
Liu J, Cao X. Cellular and molecular regulation of innate inflammatory responses. Cell Mol Immunol. 2016; 13(6):711-721. [PubMed]
Zhao K, Zhang Q, Li X, Zhao D, Liu Y, Shen Q, Yang M, Wang C, Li N, Cao X. Cytoplasmic STAT4 Promotes Antiviral Type I IFN Production by Blocking CHIP-Mediated Degradation of RIG-I. J Immunol. 2016; 196(3):1209-1217. [PubMed]
Zheng Q, Hou J, Zhou Y, Yang Y, Cao X. Type I IFN-Inducible Downregulation of MicroRNA-27a Feedback Inhibits Antiviral Innate Response by Upregulating Siglec1/TRIM27. J Immunol. 2016; 196(3):1317-1326. [PubMed]
Liu Y, Cao X. Immunosuppressive cells in tumor immune escape and metastasis. J Mol Med (Berl). 2016; 94(5):509-522. [PubMed]
Cao X. Integrative strategy for improving cancer immunotherapy. J Mol Med (Berl). 2016; 94(5):485-487. [PubMed]
Yuan M, Zhu H, Xu J, Zheng Y, Cao X, Liu Q. Tumor-Derived CXCL1 Promotes Lung Cancer Growth via Recruitment of Tumor-Associated Neutrophils. J Immunol Res. 2016; 2016:6530410. [PubMed]
Zhang X, Jiang Z, Gu Y, Liu Y, Cao X, Han Y. Inflammation-induced CD69+ Kupffer cell feedback inhibits T cell proliferation via membrane-bound TGF-β1. Sci China Life Sci. 2016; 59(12):1259-1269. [PubMed]
Tian Z, Cao X, Chen Y, Lyu Q. Regional immunity in tissue homeostasis and diseases. Sci China Life Sci. 2016; 59(12):1205-1209. [PubMed]

Zhang Q, Zhao K, Shen Q, Han Y, Gu Y, Li X, Zhao D, Liu Y, Wang C, Zhang X, Su X, Liu J, Ge W, Levine RL, Li N, Cao X. Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6. Nature. 2015; 525(7569):389-393. [PubMed]
Yang M, Chen T, Li X, Tang S, Wang C, Gu Y, Liu Y, Xu S, Li W, Zhang X, Wang J, Cao X. K33-linked polyubiquitination of Zap70 by E3 ligase Nrdp1 controls activation of CD8+ T cells. Nat Immunol. 2015; 16(12):1253-1262. [PubMed]
Cao X. A call for global research on non-communicable diseases. Lancet. 2015; 385(9967):e5-6. [PubMed]
Zheng Q, Hou J, Zhou Y, Yang Y, Xie B, Cao X. Siglec1 suppresses antiviral innate immune response by inducing TBK1 degradation via the ubiquitin ligase TRIM27. Cell Res. 2015; 25(10):1121-1136. [PubMed]
Su X, Wang H, Ge W, Yang M, Hou J, Chen T, Li N, Cao X. An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer. Cancer Res. 2015; 75(14):2875-2885. [PubMed]
Wang H, Su X, Yang M, Chen T, Hou J, Li N, Cao X. Reciprocal control of miR-197 and IL-6/STAT3 pathway reveals miR-197 as potential therapeutic target for hepatocellular carcinoma. Oncoimmunology. 2015; 4(10):e1031440. [PubMed]
Liu Y, Zhang Q, Ding Y, Li X, Zhao D, Zhao K, Guo Z, Cao X. Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip. J Immunol. 2015; 194(6):2838-2846. [PubMed]
Han Y, Jiang Z, Chen Z, Gu Y, Liu Y, Zhang X, Cao X. Pathogen-expanded CD11b+ invariant NKT cells feedback inhibit T cell proliferation via membrane-bound TGF-β1. J Autoimmun. 2015; 58:21-35. [PubMed]
Liu J, Cao X. Regulatory dendritic cells in autoimmunity: A comprehensivereview. J Autoimmun. 2015; 63:1-12. [PubMed]
Liu Y, Cao X. Intratumoral dendritic cells in the anti-tumor immune response. Cell Mol Immunol. 2015; 12(4):387-390. [PubMed]
Bao Y, Cao X. Epigenetic Control of B Cell Development and B-Cell-Related Immune Disorders. Clin Rev Allergy Immunol. 2016; 50(3):301-311. [PubMed]
Yu Z, Chen T, Cao X. Neutrophil sensing of cytoplasmic, pathogenic DNA in a cGAS-STING-independent manner. Cell Mol Immunol. 2016; 13(4):411-414. [PubMed]
Zhang Y, Cao X. Long noncoding RNAs in innate immunity. Cell Mol Immunol. 2015; 13(2):138-147. [PubMed]
Liu Y, Gu Y, Cao X. The exosomes in tumor immunity. Oncoimmunology. 2015; 4(9):e1027472. [PubMed]
Yu Z, Chen T, Cao X. RNA editing by ADAR1 marks dsRNA as "self". Cell Res. 2015; 25(12):1283-1284. [PubMed]
Lin X, Rui K, Deng J, Tian J, Wang X, Wang S, Ko KH, Jiao Z, Chan VS, Lau CS, Cao X, Lu L. Th17 cells play a critical role in the development of experimental Sjogren\'s syndrome. Ann Rheum Dis. 2015; 74(6):1302-1310. [PubMed]
Ge W, Li D, Gao Y, Cao X. The Roles of Lysosomes in Inflammation and Autoimmune Diseases. Int Rev Immunol. 2015; 34(5):415-431. [PubMed]
Zhang P, Liu X, Cao X. Extracellular pattern recognition molecules in health and diseases. Cell Mol Immunol. 2015; 12(3):255-257. [PubMed]
Tian J, Zhu T, Liu J, Guo Z, Cao X. Platelets promote allergic asthma through the expression of CD154. Cell Mol Immunol. 2015; 12(6):700-707. [PubMed]

Han Y, Chen Z, Yang Y, Jiang Z, Gu Y, Liu Y, Lin C, Pan Z, Yu Y, Jiang M, Zhou W, Cao X. Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma. Hepatology. 2014; 59(2):567-579. [PubMed]
Han Y, Yang Y, Chen Z, Jiang Z, Gu Y, Liu Y, Xu S, Lin C, Pan Z, Zhou W, Cao X. Human hepatocellular carcinoma-infiltrating CD4⁺CD69⁺Foxp3⁻ regulatory T cell suppresses T cell response via membrane-bound TGF-β1. J Mol Med (Berl). 2014; 92(5):539-550. [PubMed]
Qian C, Liu J, Cao X. Innate signaling in the inflammatory immune disorders. Cytokine Growth Factor Rev. 2014; 25(6):731-738. [PubMed]
Meng J, Liu X, Cao X. A new cytosolic DNA-recognition pathway for DNA-induced inflammatory responses. Cell Mol Immunol. 2014; 11(6):506-509. [PubMed]
Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X. IFN-γ primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b. J Immunol. 2014; 193(6):3036-3044. [PubMed]
Tang S, Chen T, Yu Z, Zhu X, Yang M, Xie B, Li N, Cao X, Wang J. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun. 2014; 5:4657. [PubMed]
Wang P, Du H, Zhou CC, Song J, Liu X, Cao X, Mehta JL, Shi Y, Su DF, Miao CY. Intracellular NAMPT-NAD+-SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors. Cardiovasc Res. 2014; 104(3):477-488. [PubMed]
Wang D, Zheng M, Qiu Y, Guo C, Ji J, Lei L, Zhang X, Liang J, Lou J, Huang W, Dong B, Wu S, Wang J, Ke Y, Cao X, Zhou YT, Lu L. Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response. J Exp Med. 2014; 211(13):2635-2649. [PubMed]
Cao X. Innovating research in China. Science. 2014; 346(6213):1035. [PubMed]
He Q, Zhang H, Wang Y, Ting HH, Yu W, Cao X, Ge W. Purified anti-CD3 × anti-HER2 bispecific antibody potentiates cytokine-induced killer cells of poor spontaneous cytotoxicity against breast cancer cells. Cell Biosci. 2014; 4(1):70.
[PubMed]
Fang H, Ang B, Xu X, Huang X, Wu Y, Sun Y, Wang W, Li N, Cao X, Wan T. TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells. Cell Mol Immunol. 2014; 11(2):150-159. [PubMed]
Gu M, Ouyang C, Lin W, Zhang T, Cao X, Xia Z, Wang X. Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation. J Immunol. 2014; 192(6):2846-2856. [PubMed]
Bao Y, Liu X, Han C, Xu S, Xie B, Zhang Q, Gu Y, Hou J, Qian L, Qian C, Han H, Cao X. Identification of IFN-γ-producing innate B cells. Cell Res. 2014; 24(2):161-176. [PubMed]
Bao Y, Cao X. The immune potential and immunopathology of cytokine-producing B cell subsets: A comprehensive review. J Autoimmun. 2014; 55:10-23. [PubMed]
Jiang Z, Han Y, Cao X. Induced pluripotent stem cell (iPSCs) and their application in immunotherapy. Cell Mol Immunol. 2014; 11(1):17-24. [PubMed]
Yao Z, Zhang Q, Li X, Zhao D, Liu Y, Zhao K, Liu Y, Wang C, Jiang M, Li N, Cao X. Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages. J Biol Chem. 2014; 289(13):9372-9379. [PubMed]
Chen T, Yang M, Yu Z, Tang S, Wang C, Zhu X, Guo J, Li N, Zhang W, Hou J, Liu H, Han C, Liu Q, Gu Y, Qian C, Wan T, Cui L, Zhu M, Zheng W, Cao X. Small GTPase RBJ Mediates Nuclear Entrapment of MEK1/MEK2 in Tumor Progression. Cancer Cell. 2014; 25(5):682-696. [PubMed]
Hou J, Zhou Y, Zheng Y, Fan J, Zhou W, Ng IO, Sun H, Qin L, Qiu S, Lee JM, Lo CM, Man K, Yang Y, Yang Y, Yang Y, Zhang Q, Zhu X, Li N, Wang Z, Ding G, Zhuang SM, Zheng L, Luo X, Xie Y, Liang A, Wang Z, Zhang M, Xia Q, Liang T, Yu Y, Cao X. Hepatic RIG-I predicts survival and interferon-α therapeutic response in hepatocellular carcinoma. Cancer Cell. 2014; 25(1):49-63. [PubMed]
Wang P, Xue Y, Han Y, Lin L, Wu C, Xu S, Jiang Z, Xu J, Liu Q, Cao X. The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science. 2014; 344(6181):310-313. [PubMed]
Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, Zhuang Y, Wu X, Yu Y, Xu T, Cao X. Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. Nat Immunol. 2014; 15(7):612-622.
[PubMed]

Chen W, Han C, Xie B, Hu X, Yu Q, Shi L, Wang Q, Li D, Wang J, Zheng P, Liu Y, Cao X. Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation. Cell. 2013; 152(3):467-478. [PubMed]
Xia M, Liu J, Wu X, Liu S, Li G, Han C, Song L, Li Z, Wang Q, Wang J, Xu T, Cao X. Histone Methyltransferase Ash1l Suppresses Interleukin-6 Production and Inflammatory Autoimmune Diseases by Inducing the Ubiquitin-Editing Enzyme A20. Immunity. 2013; 39(3):470-481. [PubMed]
Jin J, Yu Q, Han C, Hu X, Xu S,Wang Q, Wang J, Li N, Cao X. LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition. Nat Commun. 2013; 4:2075. [PubMed]
Su X, Qian C, Zhang Q, Hou J, Gu Y, Han Y, Chen Y, Jiang M, Cao X. miRNomes of haematopoietic stem cells and dendritic cells identify miR-30b as a regulator of Notch1. Nat Commun. 2013; 4:2903. [PubMed]
Liu J, Liu S, Xia M, Xu S, Wang C, Bao Y, Jiang M, Wu Y, Xu T, Cao X. Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation. Proc Natl Acad Sci USA. 2013; 110(19):7814-7819. [PubMed]
Liu X, Zhang P, Bao Y, Han Y, Wang Y, Zhang Q, Zhan Z, Meng J, Li Y, Li N, Zhang WJ, Cao X. Zinc finger protein ZBTB20 promotes toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription. Proc Natl Acad Sci USA. 2013; 110(27):11097-11102. [PubMed]
Zhang P, Liu X, Li Y, Zhu X, Zhan Z, Meng J, Li N, Cao X. Protein tyrosine phosphatase with proline-glutamine-serine-threonine-rich motifs negatively regulates TLR-triggered innate responses by selectively inhibiting IκB kinase β/NF-κB activation. J Immunol. 2013; 190(4):1685-1694. [PubMed]
Chen Z, Han Y, Gu Y, Liu Y, Jiang Z, Zhang M, Cao X. CD11c(high)CD8+ regulatory T cell feedback inhibits CD4 T cell immune response via Fas ligand-Fas pathway. J Immunol. 2013; 190(12):6145-6154. [PubMed]
Lin L, Hou J, Ma F, Wang P, Liu X, Li N, Wang J, Wang Q, Cao X. Type I IFN Inhibits Innate IL-10 Production in Macrophages through Histone Deacetylase 11 by Downregulating MicroRNA-145. J Immunol. 2013; 191(7):3896-3904. [PubMed]
Li Y, Zhang P, Wang C, Han C, Meng J, Liu X, Xu S, Li N, Wang Q, Shi X, Cao X. Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species. J Biol Chem. 2013; 288(23):16225-16234. [PubMed]
Qian C, Qian L, Yu Y, An H, Guo Z, Han Y, Chen Y, Bai Y, Wang Q, Cao X. Fas signal promotes the immunosuppressive function of regulatory dendritic cells via ERK/β-catenin pathway. J Biol Chem. 2013; 288(39):27825-27835. [PubMed]

Xu S, Liu X, Bao Y, Zhu X, Han C, Zhang P, Zhang X, Li W, Cao X. Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway. Nat Immunol. 2012; 13(6):551-559. [PubMed]
Qian L, Qian C, Chen Y, Bai Y, Bao Y, Lu L, Cao X. Regulatory dendritic cells program B cells to differentiate into CD19hiFcγIIbhi regulatory B cells through IFN-β and CD40L. Blood. 2012; 120(3):581-591. [PubMed]
Xu X, Yi H, Guo Z, Qian C, Xia S, Yao Y, Cao X. Splenic stroma-educated regulatory dendritic cells induce apoptosis of activated CD4 T cells via Fas ligand-enhanced IFN-γ and nitric oxide. J Immunol. 2012; 188(3):1168-1177. [PubMed]
Bai Y, Qian C, Qian L, Ma F, Hou J, Chen Y, Wang Q, Cao X. Integrin CD11b negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a. J Immunol. 2012; 188(11):5293-5302. [PubMed]
Wang P, Gu Y, Zhang Q, Han Y, Hou J, Lin L, Wu C, Bao Y, Su X, Jiang M, Wang Q, Li N, Cao X. Identification of resting and type I IFN-activated human NK cell miRNomes reveals microRNA-378 and microRNA-30e as negative regulators of NK cell cytotoxicity. J Immunol. 2012; 189(1):211-221. [PubMed]
Bao Y, Zheng J, Han C, Jin J, Han H, Liu Y, Lau YL, Tu W, Cao X. Tyrosine kinase Btk is required for NK cell activation. J Biol Chem. 2012; 287(28):23769-23778. [PubMed]
Qian C, Cao X. Naturally occurring CD1c+ human regulatory dendritic cells: immunoregulators that are expanded in response to E. coli infection. Eur J Immunol. 2012; 42(6):1388-1392. [PubMed]
Wang D, Zheng M, Lei L, Ji J, Yao Y, Qiu Y, Ma L, Lou J, Ouyang C, Zhang X, He Y, Chi J, Wang L, Kuang Y, Wang J, Cao X, Lu L. Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling. Nat Immunol. 2012; 13(6):560-568. [PubMed]
Yan D, Wang X, Luo L, Cao X, Ge B. Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs. Nat Immunol. 2012; 13(11):1063-1071. [PubMed]
Deng J, Liu Y, Yang M, Wang S, Zhang M, Wang X, Ko KH, Hua Z, Sun L, Cao X, Lu L. Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum. 2012; 64(11):3564-3573. [PubMed]
Liu Y, Lai L, Chen Q, Song Y, Xu S, Ma F, Wang X, Wang J, Yu H, Cao X, Wang Q. MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. J Immunol. 2012; 188(11):5500-5510. [PubMed]
Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang Q, Yang Y, Wang L, Cao X, Wang J. Activated T cell exosomes promote tumor invasion via Fas signaling pathway. J Immunol. 2012; 188(12):5954-5961. [PubMed]
Yang M, Deng J, Liu Y, Ko KH, Wang X, Jiao Z, Wang S, Hua Z, Sun L, Srivastava G, Lau CS, Cao X, Lu L. IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation. Am J Pathol. 2012; 180(6):2375-2385. [PubMed]
Li Y, Zhao LD, Tong LS, Qian SN, Ren Y, Zhang L, Ding X, Chen Y, Wang YX, Zhang W, Zeng XF, Zhang FC, Tang FL, Zhang X, Ba DN, He W, Cao XT, Lipsky PE. Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity. Arthritis Res Ther. 2012; 14(3):R123. [PubMed]
Chen Q, Wang H, Liu Y, Song Y, Lai L, Han Q, Cao X, Wang Q. Inducible microRNA-223 down-regulation promotes TLR-triggered IL-6 and IL-1β production in macrophages by targeting STAT3. PLoS One. 2012; 7(8):e42971. [PubMed]

Liu X, Zhan Z, Li D, Xu L, Ma F, Zhang P, Yao H, Cao X. Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol. 2011; 12(5):416-424. [PubMed]
Ma F, Xu S, Liu X, Zhang Q, Xu X, Liu M, Hua M, Li N, Yao H, Cao X. The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ. Nat Immunol. 2011; 12(9):861-869. [PubMed]
Hou J, Lin L, Zhou W, Wang Z, Ding G, Dong Q, Qin L, Wu X, Zheng Y, Yang Y, Tian W, Zhang Q, Wang C, Zhang Q, Zhuang SM, Zheng L, Liang A, Tao W, Cao X. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell. 2011; 19(2):232-243. [PubMed]
Zhang M, Xu S, Han Y, Cao X. Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-β. Hepatology. 2011; 53(1):306-316. [PubMed]
Xu X, Guo Z, Jiang X, Yao Y, Gao Q, Ding Y, Cao X. Regulatory dendritic cells program generation of interleukin-4-producing alternative memory CD4 T cells with suppressive activity. Blood. 2011; 117(4):1218-1227. [PubMed]
Chen T, Guo J, Yang M, Zhu X, Cao X. Chemokine-containing exosomes are released from heat-stressed tumor cells via lipid raft-dependent pathway and act as efficient tumor vaccine. J Immunol. 2011; 186(4):2219-2228. [PubMed]
Wu Y, Zhu X, Li N, Chen T, Yang M, Yao M, Liu X, Jin B, Wang X, Cao X. CMRF-35-like molecule 3 preferentially promotes TLR9-triggered proinflammatory cytokine production in macrophages by enhancing TNF receptor-associated factor 6 ubiquitination. J Immunol. 2011; 187(9):4881-4889. [PubMed]
Li D, Liu X, Lin L, Hou J, Li N, Wang C, Wang P, Zhang Q, Zhang P, Zhou W, Wang Z, Ding G, Zhuang SM, Zheng L, Tao W, Cao X. MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem. 2011; 286(42):36677-36685. [PubMed]
Li D, Liu X, Lin L, Hou J, Li N, Wang C, Wang P, Zhang Q, Zhang P, Zhou W, Wang Z, Ding G, Zhuang SM, Zheng L, Tao W, Cao X. MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem. 2011; 286(42):36677-36685. [PubMed]
Bao Y, Han Y, Chen Z, Xu S, Cao X. IFN-α-producing PDCA-1+ Siglec-H- B cells mediate innate immune defense by activating NK cells. Eur J Immunol. 2011; 41(3):657-668. [PubMed]
Zhang Y, Liu S, Yu Y, Zhang T, Liu J, Shen Q, Cao X. Immune complex enhances tolerogenecity of immature dendritic cells via FcγRIIb and promotes FcγRIIb-overexpressing dendritic cells to attenuate lupus. Eur J Immunol. 2011; 41(4):1154-1164. [PubMed]
Bao Y, Cao X. Revisiting the protective and pathogenic roles of neutrophils: Ly-6G is key! Eur J Immunol. 2011; 41(9):2535-2538. [PubMed]
Fu Q, Wu Y, Yan F, Wang N, Wang W, Cao X, Wang Y, Wan T. Efficient induction of a Her2-specific anti-tumor response by dendritic cells pulsed with a Hsp70L1-Her2(341-456) fusion protein. Cell Mol Immunol. 2011; 8(5):424-432. [PubMed]
Xiao L, Fu ZR, Liu F, Zhang LD, Shi XM, Shen XY, Ni ZJ, Fu H, Li RD, Cao XT, Ding GS, Wang QX. Suppression of allograft rejection by Tim-1-Fc through cross-linking with a novel Tim-1 binding partner on T cells. PLoS One. 2011;6(7):e21697. [PubMed]
Liu Y, Chen Q, Song Y, Lai L, Wang J, Yu H, Cao X, Wang Q. MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation. FEBS Lett. 2011; 585(12):1963-1968. [PubMed]
He D, Chen T, Yang M, Zhu X, Wang C, Cao X, Cai Z. Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association. J Mol Med (Berl). 2011; 89(2):137-150. [PubMed]

Cai Z, Zhang W, Li M, Yue Y, Yang F, Yu L, Cao X, Wang J. TGF-beta1 gene-modified, immature dendritic cells delay the development of inflammatory bowel disease by inducing CD4(+)Foxp3(+) regulatory T cells. Cell Mol Immunol. 2010; 7(1):35-43. [PubMed]
Wang D, Lou J, Ouyang C, Chen W, Liu Y, Liu X, Cao X, Wang J, Lu L. Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane. Proc Natl Acad Sci U S A. 2010; 107(31):13806-13811. [PubMed]
Yang M, Sun L, Wang S, Ko KH, Xu H, Zheng BJ, Cao X, Lu L. Novel Function of B Cell-Activating Factor in the Induction of IL-10–Producing Regulatory B Cells. J Immunol. 2010; 184(7):3321-3325. [PubMed]
Han C, Jin J, Xu S, Liu H, Li N, Cao X. Integrin CD11b negatively regulates TLR-triggered inflammatory response by activating Syk and promoting MyD88 and TRIF degradation via cbl-b. Nat Immunol. 2010; 11(8):734-742. [PubMed]
Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol. 2010; 11(6):487-494. [PubMed]
Liu X, Zahn Z, Xu L, Ma F, LiD, Guo Z, Li N, Cao X. MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα. J Immunol. 2010; 185(12):7244-7251. [PubMed]
Wang P, Hou J, Lin L, Wang C, Liu X, Li D, Ma F, Wang Z, Cao X. Inducible microRNA-155 feedback promotes type I interferon signaling in antiviral innate immunity by targeting SOCS1. J Immunol. 2010; 185(10):6226-6233. [PubMed]
Chen T, Cao X. Stress for maintaining memory: HSP70 as mobile messenger for innate immunity and adaptive immunity. Eur J Immunol. 2010; 40(6):1541-1544. [PubMed]
Qiu J, Xiao J, Han C, Li N, Shen X, Jiang H, Cao X. Potentiation of tumor necrosis factor-alpha-induced tumor cell apoptosis by a small molecule inhibitor for anti-apoptotic protein hPEBP4. J Biol Chem. 2010; 285(16):12241-12247. [PubMed]
Xu S, Han Y, Xu X, Bao Y, Zhang M, Cao X. IL-17A-producing γδT cells promote CTL responses against L.monocytogenes infection by enhancing dendritic cell cross-presentation. J Immunol. 2010; 185(10):5879-5887. [PubMed]
Ma F, Liu X, Li D, Wang P, Li N, Lu L, Cao X. MicroRNA-466l Upregulates IL-10 Expression in TLR-Triggered Macrophages by Antagonizing RNA-Binding Protein Tristetraprolin-Mediated IL-10 mRNA Degradation. J Immunol. 2010; 184(11):6053-6094. [PubMed]
Zheng Y, An H, Yao M, Hou J, Yu Y, Feng G, Cao X. Scaffolding Adaptor Protein Gab1 Is Required for TLR3/4- and RIG-I-Mediated Production of Proinflammatory Cytokines and Type I IFN in Macrophages. J Immunol. 2010; 184(11):6447-6456. [PubMed]

Hong X, Liu Y, Hu G, Zhao D, Shen J, Shen F, Cao X, Wang Q. EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma. Cancer Sci. 2009; 100(5):961-969. [PubMed]
Liu G, Liu S, Li P, Tang L, Han Y, An H, Li J, Dai X, Li N, Cao X, Yu Y. Cloning and characterization of DULP, a novel ubiquitin-like molecule from human dendritic cells.. Cell Mol Immunol 2009; 6(1):27-33. [PubMed]
Cao X. New DNA sensing pathway feeds RIG-I with RNA. Nat Immunol. 2009; 10(10):149-151. [PubMed]
Wang C, Chen T, Zhang J, Yang M, Li N, Xu X, Cao X. The E3 ubiquitin ligase Nrdp1 preferentially promotes TLR-mediated type I interferon production. Nat Immunol. 2009; 10(7):744-752. [PubMed]
Zhang M, Han Y, Han C, Xu S, Bao Y, Chen Z, Gu Y, Xia D, and Cao X. Beta2 integrin CD11b attenuates Poly I:C-induced hepatitis via negatively regulating NK cell functions. Hepatology. 2009; 50(5):1606-1616. [PubMed]
Zhang T, Liu S, Yang P, Han C, Liu J, Han Y, Wang Q, Yu Y and Cao X. Fibronectin maintains survival of mouse NK cells via CD11b/Src/β-catenin pathway. Blood. 2009; 114(19):4081-4088. [PubMed]
Hou J, Wang P, Lin L, Liu X, Ma F, An H, Wang Z, Cao X. MicroRNA-146a feedback inhibits RIG-I-dependent type I IFN production in macrophages by targeting TRAF6, IRAK1 and IRAK2. J Immunol. 2009; 183(3):2150-2158. [PubMed]
Yao M, Liu X, Li D, Chen T, Cai Z, Cao X. Late endosome/lysosome-localized Rab7b suppresses TLR9-initiated proinflammatory cytokine and type I interferon production in macrophages. J Immunol. 2009; 183(3):1751-1758. [PubMed]
Liu Q, Zhang C, Sun A, Zheng Y, Wang L, Cao X. Tumor-educated CD11bhiIalo regulatory dendritic cells suppress T cell response through arginase I. J Immunol. 2009; 182(10):6207-6216. [PubMed]
Zhang Y, Liu Q, Zhang M, Yu Y, Liu X and Cao X. Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. J Immunol. 2009; 182(6):3801-3808. [PubMed]
Chen T, Guo J, Han C, Yang M and Cao X. HSP70, released from heat stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway. J Immunol. 2009; 182(3):1449-1459. [PubMed]
Han C, Chen T, Yang M, Liu H and Cao X. Human SCAMP5, a novel secretory carrier membrane protein, fascilitates calcium-triggered cytokine secretion by interaction with SNARE machinery. J Immunol. 2009; 182(5):2986-2996. [PubMed]
Zhang Y, Liu S, Liu J, Zhang T, Shen Q, Yu Y, Cao X. Immune complex/Ig negatively regulate TLR4-triggered inflammatory response in macrophages through Fc gamma RIIb-dependent PGE2 production. J Immunol. 2009; 182(1):554-562. [PubMed]
Li H, Han Y, Guo Q, Zhang M, Cao X. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound transforming growth factor-β1. J Immunol. 2009; 182(1):240-249. [PubMed]
Han Y, Guo Q, Zhang M, Chen Z, Cao X. CD69+CD4+CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-β1. J Immunol. 2009; 182(1):111-120. [PubMed]

Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ. Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci USA. 2008; 105(31):10859-10864. [PubMed]
Cao X. Immunology in China: the past, present and future. Nat Immunol. 2008; 9(4):339-342. [PubMed]
An H, Hou J, Zhou J, Zhao Y, Xu H, Zheng Y, Yu Y, Liu S and Cao X. Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting kinase IRAK-1. Nat Immunol. 2008; 9(5):542-550. [PubMed]
Liu X, Yao M, Li N, Wang C, Zheng Y, Cao X. CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. Blood. 2008; 112(13):4961-4970. [PubMed]
Xia S, Guo Z, Xu X, Yi H and Cao X. Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells maintaining liver tolerance. Blood. 2008; 112(8):3175-3185. [PubMed]
Li L, Liu S, Zhang T, Pan W, Yang X, Cao X. Splenic stromal microenvironment negatively regulates virus-activated plasmacytoid dendritic cells through TGF-β. J Immunol. 2008; 180(5):2951-2956. [PubMed]
Li Q, Guo Z, Xu X, Xia S, and Cao X. Pulmonary stromal cells induce generation of regulatory dendritic cells attenuating T cell-mediated lung inflammation. Eur J Immunol. 2008; 38(10):2751-2761. [PubMed]
Li C, Liu Q, Li N, Chen W, Wang L, Wang Y, Yu Y and Cao X. EAPF/Phafin-2, a novel endoplasmic reticulum-associated protein, facilitates TNF-triggered cellular apoptosis through endoplasmic reticulum-mitochondrial apoptotic pathway. J Mol Med. 2008; 86(4):471-484. [PubMed]
Liu S, Wu J, Zhang T, Qian B, Wu P, Li L, Yu Y, Cao X. Complement C1q chemoattracts human dendritic cells and enhances migration of mature dendritic cells to CCL19 via activation of AKT and MAPK pathways. Mol Immunol. 2008; 46(2):242-249. [PubMed]
Xu H, An H, Hou J, Han C, Wang P, Yu Y, and Cao X. Phosphatase PTP1B negatively regulates MyD88- and TRIF-dependent proinflammatory cytokine and type I interferon production in TLR-triggered macrophages. Mol Immunol. 2008; 45(13):3545-3552. [PubMed]
Xia S, Guo Z, Yao Y, Xu X, Yi H, Xia D, Cao X. Liver stroma enhances activation of TLR3-triggered NK cells through fibronectin. Mol Immunol. 2008; 45(10):2831-2838. [PubMed]
Sun Q, Liu Q, Zheng Y and Cao X. Rapamycin suppresses TLR4-triggered IL-6 and PGE2 production of colon cancer cells by inhibiting TLR4 expression and NF-κB activation. Mol Immunol. 2008; 45(10):2929-2936. [PubMed]
Jiang Y, Chen G, Zheng Y, Lu L, Wu C, Zhang Y, Liu Q, Cao X. TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-κB pathways. Mol Immunol. 2008; 45(6):1557-1566. [PubMed]
Wu P, Wu J, Liu S, Han X, Lu J, Shi Y, Wang J, Lu L and Cao X. TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients. Clin Immunol. 2008; 129(1):40-48. [PubMed]
Liu Q, Shu X, Sun A, Sun Q, Zhang C, An H, Liu J, Cao X. Plant-derived small molecule albaconol suppresses LPS-triggered proinflammatory cytokine production and antigen presentation of dendritic cells by impairing NF-kappaB activation. Int Immunopharmacol. 2008; 8(8):1103-1111. [PubMed]
Wang L, Liu Q, Sun Q, Zhang C, Chen T, Cao X. TLR4 signaling in cancer cells promotes chemoattraction of immature dendritic cells via autocrine CCL20. Biochem Biophys Res Commun. 2008; 366(3):857-861. [PubMed]
Liu X, Zhang Y, Yu Y, Yang X, Cao X. SOCS3 promotes TLR4 response in macrophages by feedback inhibiting TGF-beta1/Smad3 signaling. Mol Immunol. 2008; 45(5):1405-1413. [PubMed]
Sun Q, Zheng Y, Liu Q and Cao X. Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation. Int Immunopharmacol. 2008; 8(13-14):1854-1858. [PubMed]

Wang Y, Chen T, Han C, He D, Liu H, An H, Cai Z, Cao X. Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Blood. 2007; 110(3):962-971. [PubMed]
Qain C, An H, Yu Y, Liu S, Cao X. TLR agonists induce regulatory dendritic cells to recruit Th1 cells via preferential IP-10 secretion and inhibit Th1 proliferation. Blood. 2007; 109(8):3308-3315. [PubMed]
Jiang Y, Chen G, Zhang Y, Lu L, Liu S and Cao X. Nerve Growth Factor Promotes TLR4 Signaling-induced Maturation of Human Dendritic Cells in vitro through Inducible p75NTR. J Immunol. 2007; 179(9): 6297-6304. [PubMed]
Rui Y, Liu X, Li N, Jiang Y, Chen G, Cao X and J Wang. PECAM-1 ligation negatively regulates TLR4 signaling in macrophages. J Immunol. 2007; 179(11):7344-7351. [PubMed]
Li N, Zheng Y, Chen W, Wang C, Liu X, He W, Xu H and Cao X. Adaptor Protein LAPF Recruits Phosphorylated p53 to Lysosomes and Triggers Lysosome destabilization in Apoptosis. Cancer Res, 2007; 67(23): 11176-11185. [PubMed]
Xiu F, Cai Z, Yang Y, Wang, X, Wang J, Cao X. Surface anchorage of superantigen SEA promotes induction of specific antitumor immune response by tumor-derived exosomes. J Mol Med, 2007, 85 (5):511-521. [PubMed]
He W, Liu Q, Wang L, Chen W, Li N, Cao X. TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Mol Immunol. 2007; 44(11):2850-2859. [PubMed]
Liu Q, Chen T, Chen G, Shu X, Sun A, Ma P, Lu L, Cao X. Triptolide impairs dendritic cell migration by inhibiting CCR7 and COX-2 expression through PI3-K/Akt and NF-κB pathways. Mol Immunol. 2007; 44 (10):2686-2696. [PubMed]
Wang Q, Li N, Wang X, Shen J, Hong X, Yu H, Zhang Y, Wan T, Zhang L, Wang J, Cao X. Membrane protein hMYADM preferentially expressed in myeloid cells is up-regulated during differentiation of stem cells and myeloid leukemia cells. Life Sci. 2007; 80(5):420-429. [PubMed]
Zhang Y, Wang X, Xiang Z, Li H, Qiu J, Sun Q, Wan T, Li N, Cao X, Wang J. Promotion of cellular migration and apoptosis resistance by a mouse eye-specific phosphatidylethanolamine-binding protein. Int J Mol Med. 2007; 19(1):55-63. [PubMed]
Han C, Chen T, Li N, Yang M, Wan T, Cao X. HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain. Biochem Biophys Res Commun. 2007; 353 (2):280-285. [PubMed]
Yan X, Xiu F, An H, Wang X, Wang J, Cao X. Fever range temperature promotes TLR4 expression and signaling in dendritic cells. Life Sci. 2007; 80(4):307-313. [PubMed]
Yang Y, Xiu F, Cai Z, Wang J, Wang Q, Fu Y, Cao X. Increased induction of antitumor response by exosomes derived from interleukin-2 gene-modified tumor cells. J Cancer Res Clin Oncol. 2007; 133(6):889-899. [PubMed]
Zhao W, An H, Zhou J, Xu H, Yu Y and Cao X. Hyperthermia differentially regulates TLR4 and TLR2-mediated innate immune response. Immunol Lett. 2007; 108(2):137-142. [PubMed]

Lam QL, Liu S, Cao X, Lu L. Involvement of leptin signaling in the survival and maturation of bone marrow-derived dendritic cells. Eur J Immunol. 2006; 36(12):3118-3130. [PubMed]
Huang X, Zhang M, Tang H, Ruo C, Cao X. Identification and characterization of DEDDL, a human-specific isoform of DEDD. Gene Expr. 2006; 13(3):141-153. [PubMed]
Chang Y, Song A, Gao Y, Shi Y, Lin X, Cao X, Lin D, Hu H. Solution structure of the ubiquitin-associated domain of human BMSC-UbP and its complex with ubiquitin. Protein Sci. 2006; 15(6):1248-1259. [PubMed]
An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X. SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity. 2006; 25(6):919-928. [PubMed]
Qian C, Jiang X, An H, Yu Y, Guo Z, Liu S, Xu H, Cao X. TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation. Blood. 2006; 108(7):2307-2315. [PubMed]
Shi L, Luo K, Xia D, Chen T, Chen G, Jiang Y, Li N, Cao X. DIgR2, dendritic cell-derived immunoglobulin receptor 2, is one representative of a family of IgSF inhibitory receptors and mediates negative regulation of dendritic cell-initiated antigen-specific T-cell responses. Blood. 2006; 108(8):2678-2686. [PubMed]
Tang H, Guo Z, Zhang M, Wang J, Chen G, Cao X. Endothelial stroma programs hematopoietic stem cells to differentiate into regulatory dendritic cells through IL- 10. Blood. 2006; 108(4):1189-1197. [PubMed]
Wang Q, Liu Y, Wang J, Ding G, Zhang W, Chen G, Zhang M, Zheng S, Cao X. Induction of allo-specific tolerance by immature dendritic cells genetically modified to express soluble TNF receptor. J Immunol. 2006; 177(4):2175-2185. [PubMed]
Chen W, Wang J, hao C, Liu S, Yu Y, Wang Q, Cao X. Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells. Eur J Immunol. 2006; 36(6):1598-1607. [PubMed]
Dai S, Zhou X, Wang B, Wang Q, Fu Y, Chen T, Wan T, Yu Y, Cao X. Enhanced induction of dendritic cell maturation and HLA-A*0201-restricted CEA-specific CD8(+) CTL response by exosomes derived from IL-18 gene-modified CEA-positive tumor cells. J Mol Med. 2006; 84(12):1067-1076. [PubMed]
Li P, Wang X, Li N, Kong H, Guo Z, Liu S, Cao X. Anti-apoptotic hPEBP4 silencing promotes TRAIL-induced apoptosis of human ovarian cancer cells by activating ERK and JNK pathways. Int J Mol Med. 2006; 18(3):505-510. [PubMed]
Sui L, Zhang W, Chen Y, Zheng Y, Wan T, Zhang W, Yang Y, Fang G, Mao J, Cao X. Human membrane protein Tim-3 facilitates hepatitis A virus entry into target cells. Int J Mol Med. 2006; 17(6):1093-1099. [PubMed]
Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochem Biophys Res Commun. 2006; 345(3):1122-1130. [PubMed]
Liu X, Li N, Wang C, Zhang X, Zheng Y, Cao X. Molecular Cloning and characterization of a novel V-ATPase associated protein, DVA9.2, from human dendritic cells. Life Sci. 2006; 79(19):1828-1838. [PubMed]

Gao Y, Song A, Shi Y, Chang Y, Liu S, Yu Y, Cao X, Lin D, Hu H. Solution structure of the ubiquitin-like domain of human DC-UbP from dendritic cells. Protein Sci. 2005; 14(8):2044-2050. [PubMed]
Huang C, Yu H, Wang Q, Yang G, Ma W, Xia D, Chen X, Yi P, Shen F, Zheng H, Cao X. A novel anticancer approach: SEA-anchored tumor cells expressing heat shock protein 70 onto the surface elicit strong anticancer efficacy. Immunol Lett. 2005; 101(1):71-80. [PubMed]
An H, Xu H, Zhang M, Zhou J, Feng T, Qian C, Qi R, and Cao X. Src homology domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through phosphatase activity- and PI-3K-independent mechanism. Blood. 2005; 105(12):4685-4692. [PubMed]
Guo Z, Zhang M, Tang H, and Cao X. Fas signal links innate and adaptive immunity by promoting dendritic cell secretion of CC and CXC chemokines. Blood. 2005; 106(6):2033-2041. [PubMed]
Wu Y, Wan T, Zhou X, Wang B, Yang F, Li N, Chen G, Dai S, Liu S, Zhang M and Cao X. Hsp70L1 Fusion Protein Enhances Induction of Carcinoembryonic Antigen-specific CD8+ CTL Response by Dendritic Cell Vaccine. Cancer Res. 2005; 65(11):4947-4954. [PubMed]
Chen H, Hou J, Jiang X, Ma S, Meng M, Wang B, Zhang M, Zhang M, Tang X, Zhang F, Wan T, Li N, Yu Y, Hu H, Yang R, He W, Wang X, Cao X. Response of Memory CD8+ T Cells to Severe Acute Respiratory Syndrome (SARS) Coronavirus in Recovered SARS Patients and Healthy Individuals. J Immunol. 2005; 175(1):591-598. [PubMed]
Dai S, Wan T, Wang B, Zhou X, Xiu F, Chen T, Wu Y and Cao X. More efficient induction of HLA-A*0201-restricted and CEA-specific CTL response by immunization with exosomes prepared from heat-stressed CEA-positive tumour cells. Clin Cancer Res. 2005; 11(20):7554-7563. [PubMed]
Wang X, Li N, Li H, Liu B, Qiu J, Chen T and Cao X. Silencing of human phosphatidylethanolamine-binding protein 4 sensitizes breast cancer cells to TNFα-induced apoptosis and cell growth arrest. Clin Cancer Res. 2005; 11(20):7545-7553. [PubMed]
Zhou J, An H, Xu H, Liu S and Cao X. Heat shock up-regulates expression of TLR2 and TLR4 in human monocytes via p38 signal pathway. Immunology. 2005; 114(4):522-530. [PubMed]
Chen W, Wang J, An H, Zhou J, Zhang L, Cao X. Heat shock up-regulates TLR9 expression in human B cells through activation of ERK and NF-κB signal pathways. Immunol Lett. 2005; 98(1):153-159. [PubMed]
He X, Wang J, Guo Z, Liu Q, Chen T, Wang X, Cao X. Requirement for ERK activation in sinomenine-induced apoptosis of macrophages. Immunol Lett. 2005; 98(1):91-96. [PubMed]
Sun H, Li N, Wang X, Chen T, Shi L, Zhang L, Wang J, Wan T, Cao X. Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells. Mol Cell Biochem. 2005; 269(1-2):85-94. [PubMed]
Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8(+) CTL response. J Cancer Res Clin Oncol. 2005; 131(7):468-478. [PubMed]

Huang C, Yu H, Wang Q, Ma W, Xia D, Yi P, Zhang L, Cao X. Potent antitumor effect elicited by superantigen-linked tumor cells transduced with heat shock protein 70 gene. Cancer Sci. 2004; 95(2):160-167. [PubMed]
Xiang Y, Sun S, Cai J, Xiang M, Tang G, Cao X. Enhancement of fractionated bone marrow transplantation on hematopoietic cell homing in a mouse allogeneic model. Transplantation. 2004; 77(7):972-978. [PubMed]
Zhang M, Tang H, Guo Z, An H, Zhu X, Song W, Guo J, Huang X, Chen T, Wang J, Cao X. Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nature Immunology. 2004; 5(11):1124-1133. [PubMed]
Han Y, Zhang M, Li N, Chen T, Zhang Y, Wan T, Cao X. KLRL1, a novel killer cell lectin-like receptor, inhibits natural killer cell cytotoxicity. Blood. 2004; 104(9):2858-2866. [PubMed]
Wang B, Chen H, Jiang X, Zhang M, Wan T, Li N, Zhou X, Wu Y, Yang F, Yu Y, Wang X, Yang R, Cao X. Identification of an HLA-A*0201-restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein. Blood. 2004; 104(1):201-206. [PubMed]
Chen T, Guo J, Yang M, Han C, Zhang M, Chen W, Liu Q, Wang J, Cao X. Cyclosporin A impairs dendritic cell migration by regulating chemokine receptor expression and inhibiting cyclooxygenase-2 expression. Blood. 2004; 103(2):413-421. [PubMed]
Wan T, Zhou X, Chen G, An H, Chen T, Zhang W, Liu S, Jiang Y, Yang F, Wu Y and Cao X. Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant. Blood. 2004; 103(5):1747-1754. [PubMed]
Sui L, Li N, Liu Q, Zhang W, Wan T, Wang B, Luo K, Sun H, Cao X. IgSF13, a novel human inhibitory receptor of the immunoglobulin superfamily, is preferentially expressed in dendritic cells and monocytes. Biochem Biophys Res Commun. 2004; 319(3):920-928. [PubMed]
Zhang M, Wang Q, Liu Y, Sun Y, Ding G, Fu Z, Min Z, Cao X. Effective induction of immune tolerance by portal venous infusion with IL-10 gene-modified immature dendritic cells leading to prolongation of allograft survival. J Mol Med. 2004; 82(4):240-249. [PubMed]
Liu Q, Chen T, Chen H, Zhang M, Li N, Lu Z, Ma P, Cao X. Triptolide (PG-490) induces apoptosis of dendritic cells through sequential p38 MAP Kinase phosphorylation and caspase 3 activation. Biochem Biophys Res Commun. 2004; 319(3):980-986. [PubMed]
Yang M, Chen T, Han C, Li N, T Wan, Cao X. Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells. Biochem Biophys Res Commun. 2004 ; 318(3):792-799. [PubMed]
Wang B, Li N, Sui L, Wu Y, Wang X, Wang Q, Xia D, Wan T and Cao X. HuBMSC-MCP, a novel member of mitochondrial carrier superfamily, enhances dendritic cell endocytosis. Biochem Biophys Res Commun. 2004; 314(1):292-300. [PubMed]
Lin N, Liu S, Li N, Wu P, An H, Yu Y, Wan T, Cao X. A novel human dendritic cell-derived C1r-like serine protease analog inhibits complement-mediated cytotoxicity. Biochem Biophys Res Commun. 2004; 321(2):329-336. [PubMed]
Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Liu Y, Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94(1-2):141-151. [PubMed]
Sun W, He X, Guo Z, Wang Q, Li X, Rayner J, Zhang L, Wang J, Cao X. IL-12p40-overexpressing immature dendritic cells induce T cell hyporesponsiveness in vitro but accelerate allograft rejection in vivo: Role of NK cell activation and interferon-gamma production. Immunol Lett. 2004; 94(3):191-199. [PubMed]

Liu X, Tian PK, Ju DW, Zhang MH, Yao M, Cao X, Gu JR. Systemic genetic transfer of p21(WAF-1) and GM-CSF utilizing of a novel oligopeptide-based EGF receptor targeting polyplex. Cancer Gene Ther. 2003; 10(7): 529-539. [PubMed]
Guo Z, Zhang M, An H, Chen W, Liu S, Guo J, Yu Y, and Cao X. Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways. Blood. 2003; 102(13):4441-4447. [PubMed]
Xu H, An H, Yu Y, Zhang M, Qi R, and Cao X. Ras participates in CpG ODN signaling through association with TLR9 and promotion of IRAK1/TRAF6 complex formation in macrophages. J Biol Chem. 2003; 278(38): 36334-36340. [PubMed]
Qi R, An H, Yu Y, Zhang M, Liu S, Xu H, Guo Z, Cheng T, Cao X. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res. 2003; 63(23): 8323-8329. [PubMed]
Liu S, Yu Y, An H, Li N, Lin N, Wang W, Zhang W, Wan T and Cao X. Cloning and identification of a novel ubiquitin-like protein, BMSC-UbP, from human bone marrow stromal cells. Immunol Lett. 2003; 86(2):169-175. [PubMed]
Xia D, Zheng S, Zhang W, He L, Wang Q, Pan J, Zhang L, Wang J and Cao X. Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen. J Mol Med. 2003; 81(9):585-596. [PubMed]
Sun W, Wang Q, Zhang L, Liu Y, Zhang M, Wang C, Wang J and Cao X. Blockade of CD40 pathway enhances the induction of immune tolerance by immature dendritic cells genetically modified to express cytotoxic T lymphocyte antigen 4 immunoglobulin. Transplantation. 2003; 76(9):1351-1359. [PubMed]
Guo J, Chen T, Wang B, Zhang M, An H, Guo Z, Yu Y, Qin Z and Cao X. Chemoattraction, adhesion and activation of natural killer cells are involved in the antitumor immune response induced by fractalkine/CX3CL1. Immunol Lett. 2003; 89(1):1-7. [PubMed]
Guo J, Zhang M, Wang B, Yuan Z, Guo Z, Chen T, Yu Y, Qin Z, Cao X. Fractalkine transgene induces T-cell-dependent antitumor immunity through chemoattraction and activation of dendritic cells. Int J Cancer. 2003; 103(2):212-220. [PubMed]
Wang Q, Zhang M, Ding G, Liu Y, Sun Y, Wang J, Zhang W, Fu Z and Cao X. Anti-ICAM-1 antibody and CTLA-4Ig synergistically enhance immature dendritic cells to induce donor-specific immune tolerance in vivo. Immunol Lett. 2003; 90(1):33-42. [PubMed]
Sui L, Zhang W, Liu Q, Chen T, Li N, Wan T, Yu M, and Cao X. Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells. Biochem Biophys Res Commun. 2003; 304(2):393-398. [PubMed]
Zhang J, Zhang W, Zhou D, Chen G, Wan T, Li N, Cao X. Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin. J Cell Biochem. 2003; 88(5):932-940. [PubMed]
Jiang Y, Wan T, Chen G, Xiu F, Xia D, Zhang W, Zhou X and Cao X. DC-CLM, a cadherin-like molecule cloned from human dendritic cells, inhibits growth of breast cancer cells. J Cancer Res Clin Oncol. 2003; 129(1):57-64. [PubMed]
Zhang J, Zhang W, Zou D, Chen G, Wan T, Zhang M and Cao X. Cloning and functional characterization of GMPR2, a novel human guanosine monophosphate reductase, which promotes the monocytic differentiation of HL-60 leukemia cells. J Cancer Res Clin Oncol. 2003; 129(2):76-83. [PubMed]
Leng J, Zhang L, Yao H, Cao X. Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma. Chin Med J (Engl). 2003; 116(10):1475-1479. [PubMed]
Sun H, Li N, Wang X, Liu S, Chen T, Zhang L, Wan T and Cao X. Molecular cloning and characterization of a novel cystatin-like molecule, CLM, from human bone marrow stromal cells. Biochem Biophys Res Commun. 2003; 301(1):176-182. [PubMed]
Liu S, An H, Li N, Yu Y, Lin N, Wan T, Zhang M, Wang W, and Cao X. Cloning and identification of a novel human ubiquitin-like protein, DC-UbP, from dendritic cells. Biochem Biophys Res Commun. 2003; 300(3):800-805. [PubMed]
Chen T, Han Y, Yang M, Zhang W, Li N, WanT, Gou J and Cao X. Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis. Biochem Biophys Res Commun. 2003; 303(4):1114-1120. [PubMed]

An H, Xu H, Yu Y, Zhang M, Qi R, Yan X, Liu S, Wang W, Guo Z, Qin Z, Cao X. Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways. Immunol Lett. 2002; 81(3):165-169. [PubMed]
Qin Z, Harders C, Cao X, Huber C, Blankenstein T, Seliger B. Increased Tumorigenicity, but Unchanged Immunogenicity, of Transporter for Antigen Presentation 1-deficient Tumors. Cancer Res. 2002; 62(10):2856-2860. [PubMed]
Liu X, Tian P, Yu Y, Yao M, Cao X, Gu J. Enhanced antitumor effect of EGF R-targeted p21WAF-1 and GM-CSF gene transfer in the established murine hepatoma by peritumoral injection. Cancer Gene Ther. 2002; 9(1):100-108. [PubMed]
Yu Y, Liu S, Wang W, Song W, Zhang M, Zhang W, Qin Z, Cao X. Involvement of tumor necrosis factor--related apoptosis-inducing ligand in enhanced cytotoxicity of lipopolysaccharide-stimulated dendritic cells to activated T cells. Immunology. 2002; 106(3):308-316. [PubMed]
Wang Q, Yu H, Zhang L, Ju D, Pan J, Xia D, Yao H, Zhang W, Wang J, Cao X. Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. J Mol Med (Berl). 2002; 80(9):585-594. [PubMed]
Sun W, Wang Q, Zhang L, Pan J, Zhang M, Lu G, Yao H, Wang J, Cao X. TGF-1 gene modified immature dendritic cells exhibit enhanced tolerogenicity but induce allograft fibrosis in vivo. J Mol Med (Berl). 2002; 80(8):514-523. [PubMed]
Zhang J, Zhang W, Zou D, Chen G, Wan T, Zhang M, Cao X. Cloning and functional characterization of ACAD-9, a novel member of human acyl-CoA dehydrogenase family. Biochem Biophys Res Commun. 2002; 297(4):1033-1042. [PubMed]
Wang Y, Wang W, Li N, Cao X. Activation of antigen presenting cells by immunostimulatory plant DNA:a natural resource for potential adjuvant. Vaccine. 2002; 201(21-22):2764-2771. [PubMed]
Guo J, Wang B, Zhang M, Chen T, Yu Y, Regulier E, Homann HE, Qin Z, Ju DW, Cao X. Macrophage-derived chemokine gene transfer results in tumor regression in murine lung carcinoma model through efficient induction of antitumor immunity. Gene Ther. 2002; 9(12):793-803. [PubMed]
Xia DJ, Zhang WP, Zheng S, Wang J, Pan JP, Wang Q, Zhang LH, Hamada H, Cao X. Lymphotactin cotransfection enhances the therapeutic efficacy of dendritic cells genetically modified with melanoma antigen gp100. Gene Ther. 2002; 9(9):592-601. [PubMed]
An H, Yu Y, Zhang M, Xu H, Qi R, Yan X, Liu S, Wang W, Guo Z, Guo J, Qin Z, Cao X. Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology. 2002; 106(1): 38-45. [PubMed]
Chen X, Tao Q, Yu H, Zhang L, Cao X. Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity. Immunol Lett. 2002; 84(2):81-86. [PubMed]
Yu Y, Tang L, Wang J, Liu S, Wang W, An H, Qi R, Zhang M, Cao X. Psoriatic lesional keratinocytes promote the maturation of human monocyte-derived langerhans cells. Dermatology. 2002; 204(2):94-99. [PubMed]

Liu S, Yu Y, Zhang M, Wang W, Cao X. The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells. J Immunol. 2001. 166(9):5407-5415. [PubMed]
Ju DW, Tao Q, Lou G, Bai M, He L, Yang Y, Cao X. Interleukin 18 transfection enhances antitumor immunity induced by dendritic cell-tumor cell conjugates. Cancer Res. 2001; 61(9):3735-3740. [PubMed]
Li N, Zhang W, Wan T, Zhang J, Chen T, Yu Y, Wang J, Cao X. Cloning and characterization of siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells. J Biol Chem. 2001; 276(30):28106-28112. [PubMed]
Zhang LH, Pan JP, Yao HP, Sun WJ, Xia DJ, Wang QQ, He L, Wang J, Cao X. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther. 2001; 8(17):1333-1342. [PubMed]
Zhang W, Wan T, Li N, Yuan Z, He L, Zhu X, Yu M, Cao X. Genetic approach to insight into the immunobiology of human dendritic cells and identification of CD84-H1, a novel CD84 homologue. Clinical Cancer Research. 2001; 7(3):822s-829s. [PubMed]
Wang Q, Zhang W, Ding G, Sun L, Chen G, Cao X. Dendritic cells support hematopoiesis of bone marrow cells. Transplantation. 2001; 72(5):891-899. [PubMed]
Zhang W, Mi J, Li N, Sui L, Wan T, Zhang J, Chen T, Cao X. Identification and characterization of DPZF, a novel human BTB/POZ Zinc finger protein sharing homotogy to BCL-6. Biochem Biophys Res Commun. 2001; 281(4):1067-1073. [PubMed]
Zhang J, Li N, Yu J, Zhang W, Cao X. Molecular Cloning and Characterization of a Novel Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor from Human Dendritic Cells. Biochem Biophys Res Commun. 2001; 285(2):229-234. [PubMed]
Luo K, Zhang W, Sui L, Li N, Zhang M, Ma X, Zhang L, Cao X. DIgR1, a novel membrane receptor of the immunoglobulin gene superfamily, is preferentially expressed by antigen-presenting cells. Biochem Biophys Res Commun. 2001; 287(1):35-41. [PubMed]
Wang Q, Yu H, Ju DW, Zhang L, He L, Cao X. Intratumoral IL-18 gene transfer improves therapeutic efficacy of antibody-targeted superantigen in established murine melanoma. Gene Ther. 2001; 8(7):542-550. [PubMed]
Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. 2001; 281(4):878-883. [PubMed]
Zhang L, Mi J, Yu Y, Yao H, Chen H, Li M, Cao X. IFN-gamma gene therapy by intrasplenic hepatocyte transplantation: a novel strategy for reversing hepatic fibrosis in Schistosoma japonicum-infected mice. Parasite Immunol. 2001; 23(1):11-17. [PubMed]
Zhang L, Ju DW, Sun Y, Tao Q, Qian S, Mi J, Hamada H, Cao X. The potent antitumor effects of combined p16 gene and GM-CSF gene therapy through efficient induction of antitumor immunity. J Cancer Res Clin Oncol. 2001; 127(2):101-108. [PubMed]
Xie Z, Cao X, Zhang W, Ye X, Yu B. Endocytic routes of exogenous antigen in murine dendritic cells and macrophages. Chinese Medical Journal. 2001; 114(1):93-96. [PubMed]
Chen W, Yu Y, Shao C, Zhang M, Wang W, Zhang L, Cao X. Enhancement of antigen-presenting ability of B lymphoma cells by immunostimulatory CpG-oligonucleotides and anti-CD40 antibody. Immunology Letters. 2001; 77(1):17-23. [PubMed]
Pan J Ju D, Wang Q, Zhang M, Xia D, Zhang L, Yu H, Cao X. Dexamethasone inhibits the antigen presentation of dendritic cells in MHC class II pathway. Immunology Letters. 2001; 76(3):153-161. [PubMed]
Huang X, Yuan Z, Chen G, Zhang M, Zhang W, Yu Y, Cao X. Cloning and characterization of a novel ITIM containing Lectin-like immunoreceptor LLIR and its two transmembrane region deletion variants. Biochem Biophys Res Commun. 2001; 281(1):131-140. [PubMed]
Yuan Z, Huang X, Zhang W, Zhang M, Wan T, Cao X. Cloning and characterization of a novel zinc finger protein (MDZF) that is associated with monocytic differentiation of acute promyelocytic leukemia cells. J Cancer Res Clin Oncol. 2001; 127(11)659-667. [PubMed]
Wang Q, Yu H, Zhang L, Ju D, Pan J, Xia D, He L, Wang J, Cao X. Vaccination with IL-18 gene-modified, superantigen-coated tumor cells elicits potent antitumor immune response. J Cancer Res Clin Oncol. 2001; 127(12):718-726. [PubMed]

Cao X, Zhang W, Wan T, He L, Chen T, Yuan Z, Ma S, Yu Y, Chen G. Molecular cloning and characterization of a novel CXC chemokine macrophage inflammatory protein-2 gamma chemoattractant for human neutrophils and dendritic cells. J Immunol. 2000; 165(5):2588-2595. [PubMed]
Ju DW, Tao Q, Cheng DS, Zhang W, Zhang M, Hamada H, Cao X. Adenovirus-mediated lymphotactin gene transfer improves therapeutic efficacy of cytosine deaminase suicide gene therapy in established murine colon carcinoma. Gene Ther. 2000; 7(4):329-338. [PubMed]
Lei H, Ju DW, Yu Y, Tao Q, Chen G, Gu S, Hamada H, Cao X. Induction of potent antitumor response by vaccination with tumor lysate-pulsed macrophages engineered to secrete macrophage colony-stimulating factor and interferon-gamma. Gene Ther. 2000; 7(8):707-713. [PubMed]
Ju DW, Yang Y, Tao Q, Song WG, He L, Chen G, Gu S, Ting CC, Cao X. Interleukin-18 gene transfer increases antitumor effects of suicide gene therapy through efficient induction of antitumor immunity. Gene Ther. 2000; 7(19):1672-1679. [PubMed]
Cao X, Huang X, Ju DW, Zhang W, Hamada H, Wang J. Enhanced antitumoral effect of adenovirus-mediated cytosine deaminase gene therapy by induction of antigen-presenting cells through stem cell factor/granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Gene Ther. 2000; 7(2):177-186. [PubMed]
Zhang W, Chen T, Wan T, He L, Li N, Yuan Z, Cao X. Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways. Biochem Biophys Res Commun. 2000; 274(3):872-879. [PubMed]
Li N, Huang X, Zhao Z, Zhang W, Yu Y, Cao X. Identification and characterization of a novel gene KE04 differentially expressed by activated human dendritic cells. Biochem Biophys Res Commun. 2000; 279(2):487-493. [PubMed]
Wang Y, Mi J, Cao X. Anti-DNA antibodies exhibit different binding motif preferences for single stranded or double stranded DAN. Immunol Lett. 2000; 73(1):29-34. [PubMed]
Li N, Zhang W, Cao X. Identification of human homologue of mouse IFN-induced protein from human dendritic cells. Immunol Lett. 2000; 74(3):221-224. [PubMed]
Huang X, Zhao Z, Yuan Z, Zhang M, Zhu X, Chen G, Cao X. Cloning and characterization of a novel deletion mutant of heterogeneous nuclear ribonucleoprotein M4 from human dendritic cells. Sci China C Life Sci. 2000; 43(6):648-654. [PubMed]
Wang Q, Cao X, Wang J, Zhang W, Tao Q, Ye T. Macrophage activation of lymphoma-bearing mice by liposome-mediated intraperitoneal IL-2 and IL-6 gene therapy. Chin Med J (Engl). 2000; 113(3):281-285. [PubMed]

Qin Z, Richter G, Schuler T, Ibe S, Cao X, Blankenstein T. B cells inhibit induction of T cell-dependent tumor immunity. Nature Medicine. 1998; 4(5):627-630. [PubMed]
Wang J, Saffold S, Cao X, Krauss J, Chen W. Eliciting T cell immunity Against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines. J Immunol. 1998; 161(10):5516-5524. [PubMed]
Cao X, Zhang W, Wang J, Zhang M, Huang X, Hamada H, Chen W. Therapy of established tumour with a hybrid cellular vaccine generated by using granulocyte-macrophage colony-stimulating factor genetically modified dendritic cells. Immunology. 1999; 97(4):616-625. [PubMed]
Cao X, Li Q,Ju DW, Wang Q, Tao Q, Wang J. Enhanced antitumor effects of bone marrow transplantation in combination with fibroblast-mediated IL-2 and IL-3 gene therapy. Transplantation. 1999; 67(9):1256-1263. [PubMed]
Zhang W, He L,Yuan Z, Xie Z,Wang J, Hamada H, Cao X. Enhanced therapeutic efficacy of tumor RNA-pulsed dendritic cells after genetic modification with lymphotactin. Hum Gene Ther. 1999; 10(7):1151-1161. [PubMed]
Zhao Z, Huang X, Li N, Zhu X, Chen S, Cao X. Direct cloning of cell differential expression genes with full-length by a new strategy based on the multiple rounds of 'long distance'polymerase chain reaction and magnetic beads mediated subtraction. J Biotechnol. 1999; 73(1):35-41. [PubMed]
Cao X, Zhang W, Wan T, Yu Y, Wang J. Enhanced antitumor immune responses of IL-2 gene-modified tumor vaccine by combination with IL-1 and low dose cyclophosphamide. J Exp Clin Cance Res. 1999; 18(2):173-179. [PubMed]
Cao X, Wang Q, Ju DW, Tao Q, Wang J. Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene. J Exp Clin Cancer Res. 1999; 18(2):191-200. [PubMed]
Ju DW, Cao X, Tao Q, Wang B, Wang T, Chen G, Yu Y. Augmentation of antitumor effect of daenovirus-mediated CD suicide gene therapy by cotransfer of interleukin 2 gene in melanoma-bearing mice. Chin Med J (Engl). 1999; 112(2):162-165. [PubMed]
Cao X, Ju DW, Tao Q, Wang J, Wan T, Wang BM, Zhang W, Hamada H. Adenovirus-mediated GM-CSF gene and cytosine deaminase gene transfer followed by 5-fluorocytosine administration elicit more potent antitumor response in tumor-bearing mice. Gene Ther. 1998; 5(8):1130-1136. [PubMed]
Cao X, Ju D, Cai R, Tao Q, Yu Y, Wang J. Effects of fibroblast-mediated interleukin 3 and interleukin 6 gene therapy on hematopoiesis in mice treated with 5-fluorouracil. J Mol Med (Berl). 1998; 76(11):782-789. [PubMed]
Cao X, Zhao Y, Yu Y, Wang Y, Zhang M, Zhang W, Wang J. Granulocyte-macrophage colony-stimulating factor induces the differentiation of murine erythroleukaemia cells into dendritic cells. Immunology. 1998; 95(1):141-147. [PubMed]
Cao X, Cai R, Ju DW, Tao Q, Yu Y, Wang J. Accelerated recovery of irradiation-induced bone marrow depression by fibroblast-mediated interleukin 6 gene therapy in combination with bone marrow transplantation in mice. Transplantation. 1998; 65(3):325-331. [PubMed]
Cao X, Cai R, Ju DW, Tao Q, Yu Y, Wang J. Augmentation of hematopoiesis by fibroblast-mediated interleukin-6 gene therapy in mice with chemotherapy. J Interferon Cytokine Res. 1998; 18(4):227-233. [PubMed]
Cao X, Zhang W, Yu Y, Tao Q, Ye T. Induction of antitumor immunity and treatment of preestablished tumors by interleukin-6-gene-transfected melanoma cells combined with low-dose IL-2. J Cancer Res Clin Oncol. 1995; 121(12):721-728. [PubMed]
Cao X, Zhang W, He L, Xie Z, Ma S, Tao Q, Yu Y, Hamada H, Wang J. Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. J Immunol. 1998; 161(11):6238-6244. [PubMed]
Ju DW, Wang B, Cao X. Adenovirus-mediated combination suicide gene and interleukin 2 gene therapy for the treatment of established tumor and induction of antitumor immunity. J Cancer Res Clin Oncol. 1998; 124(12):683-689. [PubMed]
Zhao Y, Cao X. Immune activation of erythroleukemia cells induced by interleukin 12. Science in China (Series C). 1998; 41(3):324-329. [PubMed]
Yu Y, Cao X, Lei H, Zhang M, Zhang W, Zhu X, Ye T, Wang J. Therapeutic effect on experimental metastatic tumor-bearing mice by vaccination with GM-CSF gene-modified and tumor antigen-pulsed macrophages. Science in China. 1998; 41(1):107-112. [PubMed]
DW Ju, Cao X, Arces B. Intratumoral injection of GM-CSF gene encoded recombinant vaccinia virus elicits potent antitumor response in a murine melanoma model. Cancer Gene Ther. 1997; 4(2):139-144. [PubMed]
Wan T, Cao X, Ju DW, Aces B. In vivo gene therapy of murine melanoma mediated by recombinant vaccinia virus encoding human IL-2 gene. Int J Oncol. 1997; 10(4):703-708. [PubMed]
Cao X, Wang J, Zhang W, Chen G, Kong X, Tani K. Treatment of human hepatocellular carcinoma by fibroblast-mediated human interferonαgene therapy in combination with adoptive chemoimmunotherapy. J Cancer Res Clin Oncol. 1995; 121(8):457-462. [PubMed]
Cao X, Zhang W, Ma S, Zhang M, Wang J, Ye T. Enhanced antitumor effects of tumor antigen-pulsed dendritic cells by their transfection with GM-CSF gene. Science in China. 1997; 40(5):539-545. [PubMed]
Zhang W, Cao X, Huang X, Wang J, Tao Q and Ye Tiangxing. In vivo distribution and gene expression of geneticall modified hepatocytes after intrasplenic transplantation. Science in China. 1997; 40(5):554-560. [PubMed]
Cao X, Chen G, Zhang W, Yu Y and Ye T. Enhanced efficacy of combination of IL-2 gene and IL-6 gene-transfected tumor cells in the treatment of established metastatic tumors. Gene Ther. 1996; 3(5):421-426. [PubMed]
Wang J, Cao X, Zhang W, Ye T, Tani K. Treatment of leukemia with fibroblast-mediated interferon-alpha gene therapy alone or in combination with doxorubicin. Leukemia Res. 1996; 20(5):379-384. [PubMed]
DW Ju, Cao X, Arces B. Active specific immunotherapy of pulmonary metastasis with vaccinia melanoma oncolysate prepared from granulocyte/macrophage-colony-stimulating-factor-gene-encoded vaccinia virus. J Cancer Res Clin Oncol. 1996; 122(12):716-722. [PubMed]
Cao X, Chen G, He L, Zhang W, Yu Y, Ye T. Chemoattractive effect on the effector vells of the supernatants from melanoma cells transfected with the interleukin-2(IL-2), IL-4 or IL-6 gene. J Cancer Res Clin Oncol. 1998; 124(2):88-92. [PubMed]
Cao X, Chen G, He L, Zhang W, Yu Y, Wang J. Involvement of MHC class I molecule and ICAM-1 in the enhancement of adhesion and cytotoxic susceptibility to immune effector cells of tumor cells transfected with the interleukin(IL)-2,IL-4,IL-6 gene. J Cancer Res Clin Oncol. 1997. 123(11-12):602-608. [PubMed]

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